Occupational safety and health - Science
After reading the article with the title Random or Worst Case sampling. Reflect on the article and in your own words answer the following questions. A few sentences per question should suffice. What is the main point? (5pts)Identify the purpose, impact and/or theoreticalframework of the text.What ideas stood out to me? What do I know about this topic? Where doesmy existing knowledge come from? (10 pts)How does this text help me to betterunderstand this topic or explore this field ofstudy/discipline. (5 pts)
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INDUSTRIAL HYGIENE
EXPOSURE ASSESSMENTS:
WORST-CASE VERSUS RANDOM SAMPLING
By Jerome E. Spear, CSP, CIH
T
he two types of sampling strategies to
consider when planning an exposure
assessment study are worst-case
sampling and random sampling. The broad
difference is that worst-case sampling involves
more subjectivity than a random sampling
approach.
based on the central tendency and spread (or
dispersion) of the sample distribution. Some
random sampling applications include the
following:
o
In worst-case sampling, we non-randomly
select the worker(s) who are subjectively
believed to have the highest exposure(s). If no
worst-case sample exceeds the occupational
exposure limit(s), we are subjectively satisfied
(but not statistically confident) that the exposure
profile is acceptable. For example, plant
operators who have similar job duties within a
production unit of a plant may be identified as a
similar exposure group (SEG). For such
workers, a worst-case exposure might occur on
a day that their process unit generates the
highest production output. Such a day would
subjectively be considered the worst-case
exposure period and targeted for evaluation.
o
o
Describe the 8-hour time-weighted
average (TWA) concentrations over
different days for a single worker or
SEG.
Describe the 15-minute TWA
concentrations over one workshift for a
single worker or SEG.
Estimate the full-shift TWA
concentration over one workshift based
on short-term (or grab) samples for a
single worker or SEG.
Table 1 provides a brief comparison of a worstcase sampling strategy versus a random
sampling strategy.
“Worst-case sampling involves more
A random sampling strategy requires
workers within a SEG and the sample periods to
be randomly selected. Decisions on the
acceptability of the exposure profile can then be
determined with a known level of confidence
subjectivity than a random sampling
approach.
”
Table 1 – Worst-Case Versus Random Sampling
Sampling Strategy
Worst-Case Sampling
•
•
Random Sampling
•
•
Advantages
Fewer samples are typically collected to
make a decision.
Use of statistics is not required.
Provides a method of characterizing the
exposure group with a known level of
certainty.
Considered to be a more defensible
strategy since the outcome is based on
an objective analysis.
1
© 2004 J.E. Spear Consulting, LLC
Limitations
• Relies on subjective judgments on “worstcase” exposure conditions.
• Difficult to capture the actual “worst-case
exposure period(s).
• Decisions on exposure acceptability are
made without a known level of confidence.
• More samples are required in order to
profile the exposure group.
• Takes more time to interpret the sampling
results.
random sample is one where each worker and
time period has an equal probability of being
selected for sample collection. It’s important to
collect the samples as randomly as possible;
otherwise, the resulting statistics will be
biased. A random number table and/or the
random number function in a spreadsheet
computer program (such as Microsoft Excel)
are useful tools in the random selection
process. Another consideration is, “how many
samples should be collected in order for the
exposure profile to be useful?” The answer
depends on a number of factors, including the
variability of the sample. However, AIHA
generally recommends between six and 10
samples (AIHA, 106) are needed in order to
perform a baseline exposure profile.
Exposure Profiling:
An 8-Step Process
S
tatistically speaking, there’s always a chance
of making the wrong decision no matter how
confident we are but by quantifying our level
of certainty through a random sampling strategy,
we are able to maximize our chance of making the
right decision. With the availability of computers
and software programs available today, much of
the statistical “grunt” work can be performed for us
making it easier to employ a random sampling
strategy. However, there are some statistical
terms and considerations that should be
understood, which are briefly described in the
following 8-step process to exposure profiling.
3. Measure the exposures of the randomly
1. Identify the SEG to profile.
The key
point in categorizing SEGs is to select the
exposure group in order to minimize the
amount of variation among the samples;
otherwise, the resulting confidence
intervals (calculated from the mean and
variance) will be too wide to be useful. A
SEG may be a single worker performing a
single task; however, it is often impractical
to perform random sampling for each and
every worker. So, a more practical
approach is to include multiple employees
in a SEG who have similar exposures.
For example, employees assigned to
operate propane-powered lift trucks in a
warehouse may be grouped as having
similar potential exposures to carbon
monoxide. If there are multiple SEGs
identified (as most facilities have), a
method to prioritize the data collection
needs can be devised. AIHA’s A Strategy
for Assessing and Managing Occupational
Exposures, provides a method for
prioritizing SEGs (AIIHA, 89 – 101) for
study based on the toxicity of the material,
conditions of the workplace environment
and their likelihood to influence
exposures, and individual work practices
that are likely to influence exposures.
selected workers and the randomly
selected time periods. There are three
options in collecting the data – hire an
industrial hygiene consultant to be on site to
collect the samples, collect the samples using
internal staff, and/or augment your internal
staff with an industrial hygiene consultant
where there are gaps in the required skills.
Samples do not necessarily need to be
collected by a Certified Industrial Hygienist (or
a full-time industrial hygienists for that matter).
However, if your internal staff lacks the skills
and understanding in developing a sampling
strategy and/or sampling methodologies,
consider working with a consultant who can
provide one-on-one training and instruction (as
needed), assist with the development of the
sampling strategy, and/or assist with the
interpretation the sampling data.
4. Calculate the following descriptive
statistics:
o
o
o
o
2. Randomly select workers and time periods
within the SEG selected for study. A
2
© 2004 J.E. Spear Consulting, LLC
Minimum – The minimum value in the sample
set.
Maximum – The maximum value in the
sample set.
Range – The difference between the largest
and smallest values in a sample set.
Percent above the OEL – The fraction of the
sample set (in percent) that exceeded the
occupational exposure limit.
o
o
o
o
o
Mean – The arithmetic average of a set of
data.
Median – The measurement that divides a
sample set into two equal parts.
Standard deviation – The parameter for
measuring the dispersion about the mean.
Geometric mean – The median of the
lognormally distributed data.
Geometric standard deviation – The antilog
of the standard deviation of the logtransformed
data, which measures the variability for a
lognormal distribution.
6. Calculate the following parametric
statistics:
o
o
Descriptive statistics characterize the sample’s
distribution such as the central tendency (e.g.,
mean, median, etc.) and the spread (such as the
range, standard deviation, variance, etc.).
o
5. Determine if the data fits a lognormal
and/or normal distribution. Parametric
statistics (such as upper and lower confidence
limits and tolerance limits) are statistics that
are calculated based on knowing (or
assuming) a certain underlying distribution of
the data set. The type of distribution (i.e.,
normal or lognormal) will generate different
confidence intervals and tolerance limits. Most
industrial hygiene sampling data tends to
follow a lognormal distribution. However, if the
data follows neither a lognormal nor a normal
distribution, the SEG should be redefined.
One way to qualitatively determine if the
underlying distribution follows a lognormal
and/or normal distribution is to plot the data on
probability paper. A major advantage of
probability plotting is the amount of information
that can be displayed in a compact form but it
requires subjectivity in the deciding how well
the model fits the data (Waters, Selvin, and
Rappaport 493). Probability paper is available
for various types of sample distributions and
plotting procedures are described in Technical
Appendix I of the NIOSH Occupational
Exposure Sampling Strategy Manual (Leidel,
Busch, and Lynch 97 – 105). If a statistical
program is available, a more quantitative
approach should be used to evaluate the
goodness-of-fit of the distribution. If both a
lognormal and normal distribution is indicated,
the parametric statistics should be calculated
assuming a lognormal distribution.
o
7.
3
© 2004 J.E. Spear Consulting, LLC
Estimated arithmetic mean – For a normal
distribution, the estimated arithmetic mean is
the same as the sample mean. However, for a
lognormal distribution, the arithmetic is
different and must be estimated.
UCL1,95\% of the arithmetic mean – The
UCL1,95\% is the one-side upper confidence at a
95\% confidence level. If the UCL1,95\% is below
the occupational exposure limits (OEL), we are
95\% confident that the long-term average
exposure is below the OEL. For evaluating
toxicants that produce chronic diseases, the
mean exposure should be examined
(Rappaport and Selvin 378).
95th percentile – The value in which 95\% of
the population will be included. For example,
the median is the 50th percentile.
UTL95\%,95\% – The upper tolerance limit of the
95th percentile. The UTL95\%,95\% is typically
used to examine acute (or short-term)
exposures (i.e., fast-acting contaminants).
Make a decision on the acceptability of the
exposure profile. Generally, an UCL1,95\% that
results in a value greater than the long-term
OEL suggests that the exposure profile is
unacceptable; whereas, an UCL1,95\% that
results in a value below the long-term OEL
suggests that the exposure profile is
acceptable. For chemicals with acute (or
short-term) effects, the upper tolerance limit of
the 95th percentile should be examined.
However, calculating the UTL95\%,95\% with few
data points tends to produce a wide tolerance
interval, which limits its usefulness. An
UTL95\%,95\% that results in a value below the
short-term exposure level and ceiling limit
suggests that the exposure profile is
acceptable, but large numbers of samples are
needed in order to identify “acceptable”
environments (Selvin et al. 89).
References
American Industrial Hygiene Association
(AIHA). A Strategy for Assessing and Managing
Occupational Exposures, 2nd Edition. Fairfax,
Virginia: AIHA Press, 1998.
8. Refine the SEG, if necessary. The
results of the exposure profile may
indicate that the exposure group may
need to be further refined. For example, it
may appear that the sampling for certain
individuals seem to result in higher
exposures. To statistically test the
significance of this variation, an analysis
of variance (ANOVA) may be performed.
An ANOVA is an inferential statistical test
that compares two or more means to
determine if the means are significantly
different. If the means are statistically
different, the SEG may need to be further
refined.
Leidel, N., K. Busch, and J. Lynch.
Occupational Exposure Sampling Strategy Manual
(DHEW/NIOSH Pub. 77-173). Cincinnati, Ohio:
National Institute for Occupational Safety and
Health, 1977.
Rappaport, S. and Selvin, S. “A Method for
Evaluating the Mean Exposure from a Lognormal
Distribution.” AIHA Journal. 48(1987): 374-379.
Selvin, S. S. Rappaport, R. Spear, J.
Schulman, and M. Francis. “A Note on the
Assessment of Exposure Using One-Sided
Tolerance Limits.” AIHA Journal. 48(1987): 89-93.
Two sample applications are summarized in Figure
2. The first case study involved deriving a full-shift
TWA estimate based on short-term samples. It is
important to point out that this case study does not
take into account day-to-day variation since the
samples were collected on the same day. The
second case study involves taking random
samples on multiple days, which takes into account
variations between the different workdays.
“A random sampling strategy
provides a method of
characterizing the exposure
group with a known level of
certainty.”
In summary, both worst-case sampling and
random sampling strategies are useful in
assessing exposures. However, it’s important to
understand the limitations of each and to correctly
apply the chosen sampling strategy. A primary
benefit of a random sampling strategy is that it
allows SEGs to be profiled with a known level of
certainty, which makes it a more defensible
sampling strategy.
19314 Timber Ridge Drive, Suite 100
Magnolia, Texas 77355
Phone (281) 252-0005
Email jerome.spear@jespear.com
www.jespear.com
4
© 2004 J.E. Spear Consulting, LLC
Figure 2 – Case Studies
Case Study 1 – Estimating Full-Shift Exposure Based on Short-Term Sampling Results
Sampling Strategy: The airborne exposures of two painters were evaluated during spray painting the exterior shell of an above
ground storage tank. The employees worked from the same boom-supported elevated platform. Since 1,6-hexamethylene
diisocyanate (HDI) was being aerosolized, the sampling was limited to approximately 15 minutes (based on limitations of the
sampling method) and the sampling media was placed in a desorption solution immediately following the sample collection. Due
to this limitation, the sampling strategy that was employed was to collected four random, short-term samples from the breathing
zone of each painter and estimate the full-shift airborne concentration of HDI with a certain level of confidence.
3
Applicable OELs: OSHA’s 8-hour permissible exposure limit (PEL) for HDI is 0.034 mg/m .
Descriptive statistics:
3
•
Maximum: 0.0042 mg/m
3
•
Minimum: <0.00037 mg/m
3
•
Range: 0.00394 mg/m
3
•
Mean: 0.002 mg/m
3
•
Median: 0.002 mg/m
3
•
Standard deviation: 0.001 mg/m
3
•
Geometric mean: 0.002 mg/m
3
•
Geometric standard deviation: 2.545 mg/m
Goodness-Of-Fit: Probability plotting and goodness-of-fit test indicated both a lognormal and normal distribution. As a result, the
parametric statistics (i.e., arithmetic mean and upper confidence limit) were estimated assuming a lognormal distribution.
Lognormal Parametric Statistics:
3
•
Estimated Arithmetic Mean: 0.002 mg/m
3
•
UCL1,95\% : 0.007 mg/m
Conclusion: Since the one-sided, 95\% upper control limit is below the OEL for HDI, we are 95\% confident that the actual
airborne concentration collected in the breathing zone of spray painters during this task was below the OEL. Therefore, the
estimated full-shift airborne exposure to HDI on the date of the sampling was determined to be acceptable.
Case Study 2 – Full-Shift Exposure Profile
Sampling Strategy: Random full-shift samples for formaldehyde were collected in the breathing zone of an operator forming
fiberglass-matting material. The resin used to bind the fiberglass matting contained formaldehyde. A random sampling strategy
was used to profile the exposure of the operator at this workstation.
Applicable OELs: OSHA’s 8-hour PEL for formaldehyde is 0.75 parts per million (ppm).
Descriptive statistics:
•
Maximum: 0.85 ppm
•
Minimum: 0.43 ppm
•
Range: 0.42 ppm
•
Mean: 0.624 ppm
•
Median: 0.60 ppm
•
Standard deviation: 0.15 ppm
•
Geometric mean: 0.610 ppm
•
Geometric standard deviation: 1.274 ppm
Goodness-Of-Fit: Probability plotting and goodness-of-fit test indicated both a lognormal and normal distribution. As a result, the
parametric statistics (i.e., arithmetic mean and upper confidence limit) were estimated assuming a lognormal distribution.
Lognormal Parametric Statistics:
•
Estimated Arithmetic Mean: 0.624 ppm
•
UCL1,95\% : 0.823 ppm
Conclusion: Since the one-sided, 95\% upper control limit is above the OSHA PEL for formaldehyde, we are not 95\% confident
that the long-term airborne concentrations in the breathing zones of the operators are below the OSHA PEL. Therefore, the
potential exposures are unacceptable and interventions should be provided.
5
© 2004 J.E. Spear Consulting, LLC
Theresa Stack
April 18, 1968
OSH 1970: History of OSH - Assignment: What could you do if you did not fear?
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